Biopharma Esocon 20 mg Capsule (Delayed Release) Esomeprazole

7.00৳ 

58 in stock

  • To relieve from chronic heartburn symptoms and other symptoms associated with GERD
  • For the healing of erosive esophagitis
  • For maintenance of healing of erosive esophagitis
  • In combination with amoxicillin and clarithromycin for eradication of Helicobacter pylori infection in patients with duodenal ulcer disease.
  • Zollinger-Ellison Syndrome
  • Acid related Dyspepsia
  • Duodenal & Gastric ulcer
SKU: X7096 Category:

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Description

Esocon is extensively metabolized in the liver by CYP2C19 and CYP3A4. In vitro and in vivo studies have shown that Esocon is not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4. No clinically relevant interactions with drugs metabolized by these CYP enzymes would be expected. Drug interaction studies have shown that Esocon does not have any clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin or amoxicillin.

Esocon may potentially interfere with CYP2C19, the major Esocon metabolizing enzyme. Co-administration of Esocon 30 mg and diazepam, a CYP2C19 substrate has resulted in a 45% decrease in clearance of diazepam. Increased plasma levels of diazepam have been observed 12 hours after dosing and onwards. Esocon inhibits gastric acid secretion. Therefore, Esocon may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (e.g., ketoconazole, iron salts and digoxin).

Co-administration of oral contraceptives, diazepam, phenytoin, or quinidine do not seem to change the pharmacokinetic profile of Esocon.

Combination Therapy with Clarithromycin: Co-administration of Esocon, clarithromycin, and amoxicillin has resulted in increases in the plasma levels of Esocon and 14-hydroxyclarithromycin.

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Biopharma Esocon 20mg Capsule Full Box Esomeprazole

Biopharma Esocon 20 mg Capsule (Delayed Release) Esomeprazole

7.00৳ 

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